Cellular Communication and the Cell Cycle FRQ:


a) Low extracellular pH activates TRPV1 through the binding of H + ions to TRPV1. Describe the properties, including the location, of the site of TRPV1 that allow H+ ions to bind. Describe the specific location in the cell where ATF3 protein is produced.


b) The pGoG protein is known to block the G1 to S transition in the cell cycle. Explain why this prevents mitosis from happening in the cell

Answers

Answer 1

Specifically, in sensory neurons, the plasma membrane of cells contains the cation channel protein TRPV1. Heat and low extracellular pH are only two of the many triggers that might cause it to become active.

The protein TRPV1 undergoes a conformational shift in response to the adsorption of H+ ions, opening the ion channel and allowing calcium ions to enter the cell. The subsequent signaling pathways that result in the perception of pain are activated by this calcium ion inflow.

ATF3 protein is exclusively synthesized in the cytoplasm of the cell, more particularly in the nucleus, where it is transcribed from the ATF3 gene.

The pGoG protein is known to block the G1 to S transition in the cell cycle by inhibiting the activity of the cyclin-dependent kinase (CDK) that is responsible for initiating DNA replication. This prevents mitosis from happening in the cell because, without DNA replication, the cell cannot divide.

Additionally, the pGoG protein also promotes the activity of the tumor protein p53 which is also known as the "guardian of the genome" and helps to prevent DNA damage and cell mutations, when it is activated it can stop the cell cycle and prevent mitosis from happening.

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Related Questions

Even though the finches on the various Galapagos Islands require different biotic and abiotic factors for their survival, these finches would most likely be grouped in the same

a) kingdom, but found in different ecological niches
b) population, but found in different ecosystems
c) species, but found in different habitats
d) species and found in the same biosphere

Answers

Answer:

C

Explanation:

It is C because the question says they are all finches, they just need different habitats/living conditions

Finches are most likely to grouped in the same species, but found in different habitats.

They are well known for their remarkable diversity in beak form and function.Darwin postulated that beak of an ancestral species had adapted over time to equip the finches to acquire different food resources.

Why are Darwin’s finches important?Species diverge in mate preference before genetic incompatibilities evolve.Different populations can function as biological species before they would be recognized as species solely in the basis of genetic distinctness.With the help of the finches Darwin solidify the idea of natural selection.

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An alpine area of a national park near a trail is normally covered by plants, but much of the area is now bare soil. Park rangers suspect that trampling by hikers has killed the plants. Which of the following will best test the hypothesis?
Pilihan jawaban
Counting the number of hikers leaving the trail in comparison with the number of hikers leaving other trails
Counting the number of plants along the trail in comparison with the number of plants along other trails
Comparing the number of hikers this year to the number of hikers last year on various trails
Comparing plant survivorship in areas where hikers stay on the trail with plant survivorship in the area where hikers leave the trail
Comparing the ages, heights, and weights of hikers on different trails

Answers

Comparing plant survivorship in areas where hikers stay on the trail with plant survivorship in the area where hikers leave the trail is the best test of the hypothesis.

In the western Himalayas, the threshold over which trees can no longer be found varies according to height, aspect, slope, and other factors, but is often above 3600m. This is one of the most critical zones for creatures that live at high altitudes. The Kosciuszko National Park is bordered by the Alpine National Park, which spans from middle Gippsland to the New South Wales border. Some of Australia's most beautiful alpine scenery, including mountain peaks, escarpments, and grassy high plains, may be found within the park.

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what part of a comet points most directly away from the sun?

Answers

The tail of the comet always points away from the sun no matter what direction the comet travels. Because the solar wind always blows out from the sun!

Tail

The tail actually has two parts – the dust tail and the ion tail. These can extend for millions of miles. The tail of the comet always points away from the sun no matter what direction the comet travels because the solar wind always blows out from the sun.

Which scientists labeled the DNA and proteins of viruses to demonstrate that DNA is the molecule of heredity

Answers

In 1953, James Watson and Francis Crick proposed the double helix model of DNA, which revolutionized the field of genetics. The discovery of the structure of DNA was a monumental achievement, it  was important breakthrough in establishing DNA as the molecule of heredity.

In 1935, American microbiologist Wendell Stanley demonstrated that a virus is composed of proteins and nucleic acids, proving that viruses are complex, living organisms. Stanley also identified and labeled the proteins and nucleic acids of the virus he was studying, which allowed him to conclude that the nucleus of this virus was composed of DNA. This was the first time that a scientist had identified and labeled the DNA and proteins of a virus, and it demonstrated that DNA is the molecule of heredity.

In the 1940s, American virologist Alfred Hershey and Canadian biologist Martha Chase conducted a series of experiments to study the composition of viruses. They used a radioactive isotope of phosphorus to label the proteins of a virus, and a radioactive isotope of sulfur to label the DNA. By doing this, they were able to prove that the DNA of the virus was the molecule responsible for heredity. This was the first time that scientists had labeled the DNA and proteins of a virus to demonstrate that DNA is the molecule of heredity.

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Which hypersensitivity reaction is antibody-dependent and includes the immediate cytotoxic response seen in maternal-fetal Rh incompatibility or mismatched blood transfusion

Answers

When antibodies are involved in an immune response, it's known as a type II hypersensitivity reaction (IgG or IgM) are directed against extracellular matrix antigens and cause cellular death, functional loss, or tissue damage.

When IgG or IgM antibodies bind to an antigen on the surface of a cell, other immune cells and complements attack the antigen, causing the cell to be destroyed. This is known as a type II, or cytotoxic, hypersensitivity reaction. During the transmission of incompatible maternal antibodies to foetal red blood cellular, a condition known as erythroblastosis fetalis, which results in hemolytic anaemia in the foetus, complement-dependent type II hypersensitivity can also happen.

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What is rate of change of position at a specific point in time?

Answers

Answer:

instantaneous speed. the rate of change in position at a given point in time. velocity. the speed of an object and the direction of its motion.

Once pyruvate is produced in glycolysis, the cell has two choices, without oxygen which option does it NOT have? A. Oxidative phosphorylation C. Anaerobic respiration B. Alcoholic fermentation D. Lactic acid fermentation​

Answers

Once pyruvate is produced in glycolysis, cell has two choices, without oxygen, option that it does not have: A.) Oxidative phosphorylation. It is the final stage of aerobic cellular respiration.

What happens to pyruvate after glycolysis without oxygen?

When oxygen is not present, pyruvate undergoes a process called fermentation. In the process of fermentation, NADH + H+ from glycolysis will be recycled back to NAD+ so that glycolysis can continue. In the glycolysis, NAD+ is reduced to form NADH + H+.

If insufficient oxygen is available, acid is broken down anaerobically, producing lactate in animals and ethanol in plants and microorganisms.

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In the ________ temperature scale, water freezes at 0° and boils at 100°.
Celsius
Kelvin
Fahrenheit

Answers

Answer:

Celsius is the correct answer

What are the two factors that may affect active site and enzyme function?

Answers

The first factor is temperature; normally, a reaction is sped up or slowed down depending on the temperature. The second factor is pH; each enzyme has a preferred pH range. these two factors affect the active site and enzyme function.

What is temperature?

The average kinetic energy of a system is measured by its temperature. The kinetic energy of a system starts to rise as the particle's velocity increases, which raises the system's temperature. The energy that is transferred when two bodies with different surface temperatures come in touch is referred to as heat.

What are enzymes?

Proteins called enzymes serve as biological catalysts by quickening chemical reactions. Substrates are the molecules that enzymes can interact with, and the enzyme changes the substrates into other molecules known as products.

What is the active site?

The area of an enzyme where substrate molecules bind and undergo a chemical reaction is known as the active site. The amino acid residues that make up the active site are those that catalyze the reaction of the substrate and those that temporarily binds with the substrate.

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14. Radioactive or radiometric dating is used to
determine the ____
age of rocks

Answers

Answer:

The correct answer is - precise.

Explanation:

Radiometric dating or radioactive dating used to determine the precise age of rocks or fossils. It is also known as absolute dating. This uses radioactive minerals found in the rocks or fossils similar to the geological clock.

The radiometric method on the basis of the mineral can be used to determine the different ages of rocks. For instance, Carbon dating used to determine up to 50000 years old rocks whereas Uranium–lead dating, used to date rocks that formed between 1 million years to over 4.5 billion years ago.

is cell wall or cell membrane is living organle​

Answers

Answer:

membrane i had this question a few days ago

Explanation:

what are SHE concepts

Answers

The four SHE Key concepts: Communication and Collaboration, Development, Influence, and Application and Limitation.

Answer:

Hello There!!

Explanation:

The answer is=>There are four she concepts that are=Communication and Collaboration, Development, Influence, Application and Limitation.

hope this helps,have a great day!!

~Pinky~

Synthesize In your own words, explain the effect of sea otters on kelp forests, and what
Estes's findings suggest about managing predator-pray relationships in local environments.

Answers

A kelp forest can be safeguarded by the presence of sea otters. They consume a lot of sea urchins, which controls their population and keeps the kelp forest from being destroyed. One of the foundational species of the coastal ecology is the sea otter.

What Are sea otters?

Marine animals known as sea otters (Enhydra lutris) live along the coasts of the Aleutian Islands and North America's mainland up to Mexico.. Fish, sea urchins, mollusks, and crustaceans make up the majority of sea otters' diets.  Sea otters are keystone species is one that has a significant, calming effect on the entire ecological community.

Sea otters are a keystone species that keeps kelp forest ecosystems in a healthy balance in addition to regulating populations of ravenous kelp grazers.To prevent floating away in the churning sea while they sleep, sea otters prefer to anchor in kelp or large seaweed. To keep each other company, they share this quality. They stick within the group as a result to keep from vanishing into the distance.It's thought that sea otters contributed to the preservation of kelp forests. This reduces the degradation of the kelp forest and helps control the population in addition to eating a lot of sea urchins. A keystone species, sea otters are crucial to the ecosystem of the coastal region.Sea otters, a form of plankton, can put pressure on sea urchins by consuming and grazing on them. Because sea urchins are grazers of kelp and are a species of plankton, sea otters can consume them and graze on them. As kelp is subjected to less grazing pressure due to the decreased urchin density, kelp forests can grow in the presence of sea otters.Kelp forests

A versatile sea vegetable, kelp can be eaten raw, cooked, or as a component of several supplements. Sushi, salads, sauces, and other dishes must all have kelp. Particularly sea otters are essential to the health of kelp forests, which are essential to the health of the bay. Sea urchins, which may completely devastate kelp beds without them, instead eat the stripes of huge kelp plants, which are not consumed by sea otters.

The Significance Of Sea Otters In Alaska’s Kelp Forests

Sea otters play a key part in the kelp forests around the coast of Alaska. More than 20 distinct species of fish live in kelp forests, which also serve as spawning and breeding grounds for herring, atka mackerel, and salmon fry nurseries. Sea otters contribute to the energy flow between the ocean and kelp forest. Sea otters feed on kelp forests because they are dense, which opens up the canopy to let sunlight reach the floor and feed herbivores. Because sea otters graze on urchins, a primary pest in kelp forests, the urchin population is impacted, which harms the canopy of kelp forests.

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The anthropologit i attending the annual conference of the American Aociation of Phyical Anthropologit (AAPA) and he i chatting with another paleoanthropologit named Jane who work at a nearby foil ite in Eatern Africa. Jane ak if he will hare hi foil data with her o he can compare the information uncovered at thi ite, and he worrie that haring the data with Jane will undermine hi authority in the dicipline. How hould he proceed?

Answers

The anthropologist needs to consider the advantages and disadvantages of giving Jane access to his data. On the one hand, the data sharing could result in new discoveries and partnerships that could advance the study of paleoanthropology.

However, if Jane were to publish results based on his data before he does, it might also jeopardize his standing in the field. In the end, he should decide whether to disclose the data based on what he thinks will advance knowledge and understanding in the profession, not on concerns about personal power.

He may want to consider discussing his concerns with his colleagues or mentors before making a decision. It's also important to have a clear agreement about authorship, data usage, and recognition of the data source.

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If a man with O blood marries a woman with AB blood, what is the chance that their child will be O blood? Please show a punnet square.

Answers

Answer:

I think its a 0% chance because

xA xB

xi Ai Bi

y A B

Explanation:

Which of the following is a condition for which a person might take antianxiety drugs?Immersive Reader
(1 Point)

A.drowsiness

B.dizziness

C.alcohol withdrawal

D.schizophrenia

Answers

I believe c is the answer

What is ATP and ADP?

Answers

Answer:

Adenosine diphosphate

Chemical compound Adenosine diphosphate, also known as adenosine pyrophosphate, is an important organic compound in metabolism and is essential to the flow of energy in living cells.

Answer:

ATP (Adenosine tri-phosphate) is an important molecule found in all living things. Think of it as the “energy currency” of the cell. If a cell needs to spend energy to accomplish a task, the ATP molecule splits off one of its three phosphates, becoming ADP (Adenosine di-phosphate) + phosphate.

Explanation:

I need help, thx lads

Answers

i did'nt understod ur question

PLEASEEEEEEE HELP GUYS THIS MY FIRST BTOLOGY CLASS!! 2

Answers

The equation of line when a line passes through a point (-2, 7) and have slope 5, is y = 5x + 17> The blank words are slope, point, b in order.

What is a slope?

In mathematics, a line's slope, also known as its gradient, is a numerical representation of the line's steepness and direction

Given:

Slope m = 5

And point (-2, 7)

Slope-intercept form: y = mx + b

If a line passes through a point (x₁ ,y₁) and have slope m

then the equation of line is

y - y₁ = m (x - x₁)

Substituting the values,

y - 7 = 5(x + 2)

Simplifying,

y = 5x + 17

Therefore, the equation is y = 5x + 17.

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The growth of the human population directly relates to the
use of natural resources by humans.
Growth of Human Population over History

Based on the graph, which two statements about human use of natural
resources are most likely true?

Answers

Answer:

C

Explanation:

8.
How do animal and plant viruses acquire an envelope?
A.
They synthesise it.
B. From the culture growth medium
C.
D.
E. It is part of a wall of the bacterial cell.
From the nuclear membrane of the host cell
They take it from other viruses.

Answers

Cellular membranes in a process called budding animal and plant viruses acquire an envelope.

What is an envelop?

The cell membrane, cell wall, and outer membrane, if present, make up the cell envelope. Typically, prokaryotes like bacteria exhibit this envelope. It consists of a bacterium's cell wall and inner cell wall. The integrity of the cell's structure is provided by the cell envelope.

The cell wall, the cell membrane, and any outside membrane that may be present make up the cell envelope. The cytoplasmic membrane, cell wall, and capsule make up the cell envelope in Gram-positive bacteria with a single membrane.

The complex, dynamic, multilayered cell envelope serves to shield bacteria from their uncontrollable and frequently hostile surroundings. Most bacteria's cell walls can be divided into one of two categories.

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What caused the Earth's axis to become tilted? *

Answers

Answer:

long ago, when Earth was young, it is thought that something big hit Earth and knocked it off-kilter. So instead of rotating with its axis straight up and down, it leans over a bit. By the way, that big thing that hit Earth is called Theia.

Explanation:

Answer:

This tilt was caused by a collision with an Earth-sized planet billions of years ago; called Theia.

I
|
1. What is the mRNA strand that would be copied from this DNA strand?
GGC TAT ATC CTG CGCTAT ACG CIA

Answers

Answer
CCG AUA UAG GAC GCGAUA UGC G?U

?=there is no such thing as an I in a DNA strand.
C= G
G= C
A=U
T= A

Hope this helps

Ligaments ere very strong but resistant to stretch Which protein fiber probably predominates?
a. Collagen b. Elastic c. Reticular d. Adipose

Answers

Ligaments are extremely strong but not stretchable. Most likely, collagen protein fiber is predominant.

Which of the aforementioned structures resists stretching?

The primary structural element of connective tissue, collagens withstand tensile or stretching stresses. There are about 40 different forms of collagens, but four of them are the most prevalent.

What distinguishes the holocrine gland from the merocrine and apocrine secretions?

Products are produced and then secreted by merocrine glands. Apocrine gland cells store its fluids until they rupture and discharge their contents, whereas apocrine gland cells release secretions by clamping off the apex region of the cell. In this instance, the cell joins the secretion.

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HELP!!!
Considering the origins and processes involved in how natural gas, petroleum, and coal formed, which of the following is the best explanation regarding
why these resources are referred to as fossil fuels?
Natural gas, petroleum, and coal were formed by breaking open rocks that contain fossils from millions of years ago.
Natural gas, petroleum, and coal were only formed during the Jurassic period when dinosaurs walked the Earth.
Natural gas, petroleum, and coal were formed when organic matter that has been buried deep in the Earth was subjected to heat and pressure
over millions of years.
Natural gas, petroleum, and coal were formed when elements came together to form planet Earth billions of years ago.

Answers

Answer:

The fossil fuels on Earth were formed well before the presence of dinosaurs, which is why they are called fossil fuels. Fossil fuels were formed in the Earth's crust out of dead organisms that lived hundreds of millions of years ago

Explanation:

Number 3 is ur answer  :)

in what tissues, cells and organ does ependymoma first start

Answers

It begins in the spinal cord or brain

How does natural selection lead to increases and decreases of specific traits?

Answers

More individuals with beneficial mutations will survive than those without it, and it will lead to an increase in the expression of those certain traits throughout the population through increases and decreases of specific traits.

Any modification to a species' structure or behavior that makes it more suited to surviving and procreating in its environment is referred to as an adaptation. Random mutations can cause the expression of particular features to become more prominent. Natural selection will result in an increase in the expression of specific features throughout the population since more people with advantageous mutations will survive than those without them.

Physical characteristics of an organism, such as the bill on a bird or the fur on a bear, are examples of structural adaptations. Behavioral adjustments make up the rest. Organisms use behavioral adaptations to help them survive. Bird migration and calls are two examples of behavioral adaptations.

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how does the the UN Decade on Ecosystem Restoration connect with the 2030 Agenda for Sustainable Development

Answers

Decade is closely aligned with the 2030 Agenda for Sustainable Development which outlines 17 Sustainable Development Goals that aim to achieve a more sustainable and equitable world for all.

The Decade focuses on the restoration of degraded ecosystems, which is essential for the achievement of the Sustainable Development Goals. Ecosystems are essential for the health and vitality of the planet and its inhabitants. They provide a variety of resources such as food, water, and medicine, and they regulate the climate and provide habitat for many species of plants and animals. When these ecosystems are degraded, they can no longer provide these essential resources and services.

The Decade on Ecosystem Restoration seeks to address this problem by focusing on the restoration of these ecosystems. This includes activities such as reforestation, restoring wetlands, and rehabilitating degraded land. These activities not only help restore ecosystems, but they also help reduce poverty and improve the livelihoods of people living in these areas. For example, restoring wetlands can help provide water for irrigation, while rehabilitating degraded land can help improve crop yields and provide more income for local communities.

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Caribou live near the North Pole. During the winter,
caribou use their hooves to scrape away snow to
get at the small plants they eat. There are very few
trees in the biome where caribou live.
In which biome do caribou live?
A. Temperate forest
B. Savanna
C. Tundra
D. Chaparral

Answers

Answer:c

Explanation:

These pea plants have been in the sunlight since early morning.

What can the pea plants do because they are in sunlight? What does this mean for the number of energy storage molecules in the pea plants?

The pea plants can…
Responses

Answers

With the help of photosynthesis, the pea plants can take in carbon from the air. The carbon is used to make energy storage molecules.

What do you mean by photosynthesis?

Photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that, through cellular respiration, can later be released to fuel the organism's activities.

The energy from light causes a chemical reaction that breaks down the molecules of carbon dioxide and water and reorganizes them to make the sugar (glucose) and oxygen gas.

The main purpose of photosynthesis is to convert radiant energy from the sun into chemical energy that can be used for food. Cellular respiration is the process that occurs in the mitochondria of organisms (animals and plants) to break down sugar.

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Times Inc. is trying to develop an asset-financing plan. The firm has $540,000 in temporary current assets and $440,000 in permanent current assets. Times also has $640,000 in fixed assets. Assume a tax rate of 40 percent. (Do not round intermediate calculations. Round your answers to the nearest whole number.) a. Construct two alternative financing plans for Times. One of the plans should be conservative, with 80 percent of assets financed by long-term sources, and the other should be aggressive, with only 56.25 percent of assets financed by long-term sources. The current interest rate is 14 percent on long-term funds and 8 percent on short-term financing. Compute the annual interest payments under each plan. Annual Interest Conservative $ Aggressive $ b. Given that Times' earnings before interest and taxes are $420,000, calculate earnings after taxes for each of your alternatives. Earnings After Taxes Conservative $ Aggressive $ c. What would the annual interest and earnings after taxes for the conservative and aggressive strategies be if the short-term and long-term interest rates were reversed Gloria McGraw, a patient at Broadmoor Medical Clinic, underwent an arthroscopic surgical procedure of her right knee. Dr. Jones's fee for this procedure was $1400; however, the claim payment from her insurance carrier was reduced to $1100 because of UCR provisions. Ms. McGraw doesn't understand why this occurred and asks you to explain. What do you tell her? What are the 4 most important environmental factors that influence bacterial growth? round your answer to the nearest hundredth. Based on the videos and the reading material, how would you define a data scientist and data science?As discussed in the videos and the reading material, data science can be applied to problems across different industries. Give a brief explanation describing what industry you are passionate about and would like to pursue a data science career in?Based on the videos and the reading material, what are the ten main components of a report that would be delivered at the end of a data science project? 5. The picture shows a mass that is attached to a spring with constant, K = 500 N/m(20 points)The mass is of 2 kg and the values of the heights are:h1= 5 meters,h2= 10 meters andh3= 2 meters.The spring is compressed a length of 80 cm. What is the speed of the mass when it reaches a height of h2?What is the speed of the mass when it reaches a heighth3? How do you do comparative shopping? The route labeled Z is also known as the Which table(s) could represent the production rate of factory E? modern life? What comment do the events in the story make on in house taken over Find the Input force, if the Mechanical Advantage of the simple machine used is 5 and Output force is 50 N. P.S PLEASE DO NOT POST A LINK THAT I HAVE TO DOWNLOAD EVERY TIME I ASK A QUESTION PEOPLE POST THAT JUST POST A WRITEN ANSWER WITH AN EXPLINATION THAT IS ALL a friend of yours confided in you that he intends to Dropout of school to get married write a letter to her giving her at least three reasons why she need to stay at school (write in essay form) A teacher wants to check the typing proficiency of five students. She gives all of them the same passage to type. Which student is likely to be accurate in the typing test Separation of mixtures and purification of chemical substances Is .gov a reliable source? Focus Assignment1. Describe two learning activities you might employ that could help transfer Josh's abilityto focus on digital media to other activities. Describe one activity designed to help Joshdevelop a sense of trust and safety when engaging in play with other students. Observeand record the content that Josh favors. What activities/materials could these interestsbe transferred to? Observe and record the situations where Josh shows a lack of trustand a concern for safety. needs 4 more crowns give 40 points to them give four easy awnsers Hi, I have a CodeHS Python assignment called "Exclamation Points"the assignment is as follows and I have no idea where to start with this if someone could help me please:"Words are way more edgy when you replace the letter i with an exclamation point!Write the function exclamations that takes a string and then returns the same string with every lowercase i replaced with an exclamation point. Your function should:Convert the initial string to a listUse a for loop to go through your list element by elementWhenever you see a lowercase i, replace it with an exclamation point in the listReturn the stringified version of the list when your for loop is finished" A container has cups of milk in it. The container is 1/3 full. How many cups does the container hold? Explain or show your reasoning. MATH 1. Solve for x: 2x + 8 = 180 x=2.Solve for x: 3x - 3 = 90 x=3.Solve for x: 2x - 5 + x - 7 = 180 x=4.Solve for x: x + 1 + x + 4 + x - 2 = 90 x=