Why are camels the best form of transport across the desert

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Answer 1

Answer :Reason why a camel is the best form of transportation across the desert  : (a) It has a unique ability to survive for long without food and water. (b) They have an incredible water storage capacity, they do not sweat lose much moisture. (c) They have broad padded, two toed feet ideal for walking on desert sand.


Related Questions

what was a result of the commercial revolution

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Explanation:

The Commercial Revolution, which occurred in Europe between the 16th and 18th centuries, had several significant results, including:

Expansion of trade and commerce: The Commercial Revolution led to an increase in international trade and commerce, as European countries began to establish colonies and trade networks in Asia, Africa, and the Americas. This led to the growth of merchant and banking classes, as well as the development of new forms of business organization, such as joint-stock companies.

Development of capitalism: The Commercial Revolution helped to lay the foundations of modern capitalism, as merchants and entrepreneurs pursued profits through investment in trade and commerce. This led to the growth of wage labor and the emergence of industrial capitalism, as entrepreneurs invested in new technologies and manufacturing processes.

Increase in wealth and economic growth: The Commercial Revolution contributed to a significant increase in wealth and economic growth in Europe, as trade and commerce expanded and new markets were opened up. This helped to fuel the growth of cities and the development of new industries, such as textiles and shipping.

Growth of imperialism: The Commercial Revolution also played a significant role in the growth of European imperialism, as European countries sought to establish colonies and trade networks around the world. This led to the exploitation of natural resources and labor in these colonies, as well as the spread of European culture and values.

Development of international trade and finance: The Commercial Revolution led to the growth of international trade and finance, as European countries established trade networks and banking systems around the world. This helped to lay the foundations for the modern global economy, as well as the development of international financial institutions, such as the World Bank and International Monetary Fund.

What happened shortly after the United States and north Vietnam signed a peace accord 0roviding for the withdrawal of the American troops from Vietnam

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Answer:

Two months after the signing of the Vietnam peace agreement, the last U.S. combat troops leave South Vietnam as Hanoi frees many of the remaining American prisoners of war held in North Vietnam.

Explanation:

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SERVING WITH THE WOMEN'S ARMY CORPS number 1

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"Serving with the Women's Army Corps" was a popular recruitment slogan used during World War II by the United States Army to encourage women to join the Women's Army Corps (WAC).

The Women's Army Corps (WAC) was created in 1942 as a branch of the U.S. Army to allow women to serve in non-combat roles during the war, thus freeing up men for combat duty. The WAC played a vital role in supporting the war effort by filling positions in clerical work, communications, logistics, and other support roles. The Women's Army Corps offered women the opportunity to serve their country in a variety of ways, both at home and abroad. Women who joined the WAC went through basic training, and many received specialized training in fields such as administration, communications, and motor pool operations. WAC members served in the United States and in various overseas locations, including Europe, the Pacific, and North Africa. The WAC provided women with new opportunities for personal and professional growth, and many women found the experience to be rewarding and fulfilling. However, they also faced challenges and discrimination as they navigated a traditionally male-dominated military environment. Despite these challenges, the WAC was a significant milestone in the history of women's military service in the United States, and it paved the way for increased opportunities for women in the military in the decades that followed. The slogan "Serving with the Women's Army Corps" symbolized the pride and dedication of the women who served in the WAC during World War II, and it remains a testament to the contributions of women to the U.S. military and their role in breaking gender barriers in the armed forces. Today, women continue to serve in diverse roles within the U.S. military, including combat positions, and their contributions are valued and honored. The Women's Army Corps played a significant role in advancing the status of women in the military and opening doors for future generations of women who serve in the armed forces.  Overall, "Serving with the Women's Army Corps" represents a historic chapter in the ongoing struggle for gender equality and women's rights.

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W.E.B. Du Bois's strategy for African Americans at the turn of the
twentieth century was superior to Booker T. Washington's because

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Answer:

Du Bois believed in demanding full civil rights and equality for African Americans, while Washington's strategy was based on accommodation and gradualism, which perpetuated segregation and inequality. Additionally, Du Bois advocated for higher education and political representation for African Americans.

Explanation:

William Seward insisted that the Union wait to issue the Emancipation Proclamation until:

A- the War was over

B- a decisive vicory

C- the defeat of Robert E Lee's army

D- Lincoln had recovered from illness

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Your answer is B- a decisive victory

NEED HELP WILL GIVE BRAINLIEST AND 5 STARS I HAVE 30 MINUTES.

Answers

Answer:

A conservative would most likely say they would lower taxes and reduce government including government debt.

A socialist on the other hand would most likely say they would want an economic arrangement that could serve society all in one.

A democratic would support government spending and higher rates and spending less on common defense.

Explanation:

Name atleast one of Alexander the Great’s bad military accomplishments

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One of Alexander the Great's bad military accomplishments was his failed invasion of India. After conquering much of the Persian Empire, Alexander turned his sights eastward and led his army across the Hindu Kush mountains into northern India in 327 BC. However, his campaign was met with fierce resistance from Indian kingdoms, and his troops suffered heavy losses from battles, disease, and harsh terrain. Despite winning some notable victories, including the Battle of the Hydaspes River against King Porus, Alexander's army was eventually forced to turn back due to lack of supplies and mounting casualties. The campaign in India drained Alexander's resources and manpower and weakened his hold on his conquered territories, leading some of his officers to mutiny and demand to return home.

Plssss answer this for me

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One example of how Reconstruction worked to build a better society in the South was the establishment of the Freedmen's Bureau.

What is Reconstruction?

Reconstruction was a period in United States history following the Civil War that lasted from 1865 to 1877. It was a time when the nation was rebuilding itself after being divided by slavery.

This organization provided food, housing, medical care, and schooling for freed slaves. By providing former slaves with these basic necessities, the Freedmen's Bureau helped them transition from slavery to independence, which was a key factor in helping them to create a better life for themselves in the post-Civil War south. Another example of how Reconstruction worked to build a better society in the South was the passage of the 14th Amendment, which guaranteed the civil rights of all citizens. This amendment provided freed slaves with equal protection under the law and the right to vote, which allowed them to become more active in their communities and create a more equitable society. This amendment also helped to end the system of racial discrimination that had been in place prior to the Civil War. By establishing legal protections for all citizens, Reconstruction helped to create a more just and equitable society in the post-Civil War south.

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President Eisenhower viewed the construction of an interstate highway system as important ______.

a. for national defense

b. to help the auto industry

c. to boost the homebuilding industry

d. to provide employment opportunities

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a. for national defense

Need help. Please read everything and answer accordingly. I will give brainliest and 5 stars to a descriptive answer. I have 30 minutes so please help out. :)

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Thomas Hobbes and John Locke were two of the most influential political philosophers of the modern era. While they had many differences, both were concerned with the nature of government and the relationship between the government and the people. If you were to ask Hobbes and Locke about their thoughts on the state of American democracy and the structure of the US government, their responses might be as follows:

Thomas Hobbes: Hobbes was a proponent of the idea that people are naturally selfish and violent, and that life in a state of nature is "solitary, poor, nasty, brutish, and short." According to Hobbes, the only way to escape this state of nature is to create a strong, centralized government that has the power to maintain order and enforce laws. Hobbes would likely view the US government as a necessary evil, but he would be skeptical of the idea of democracy, since he believed that people are not capable of governing themselves. He would argue that a strong executive branch, with the power to maintain order and protect citizens from each other, is necessary for a stable society.

John Locke: Locke, on the other hand, believed that people are naturally rational and moral, and that the purpose of government is to protect the natural rights of its citizens. Locke argued that government should be limited in its power, and that citizens should have the right to rebel against a government that violates their natural rights. Locke would likely view the US government as a positive example of a democratic government, but he would be critical of any attempts to limit individual rights or concentrate too much power in the hands of the government. He would argue that the US government should be structured in a way that protects the natural rights of its citizens, and that the people should have the ability to hold their leaders accountable if they fail to do so.

In summary, while Hobbes and Locke had different views on the nature of humanity and the role of government, they both believed that government was necessary to maintain order and protect citizens. Hobbes would likely be skeptical of the idea of democracy and argue for a strong executive branch, while Locke would support a democratic government that protects the natural rights of its citizens and is accountable to them.

i need help i need to answer this in order please


here is the picture


just ignore that part that says evaluate 2 other students.


But i need to follow all the instructions please.

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The Cult of True Womanhood, also known as the Cult of Domesticity, was a set of beliefs and values that arose in the 19th century in the United States and emphasized the importance of women's roles in the home.

What were the virtues espoused by the Cult of True Womanhood ?

One of the key tenets of the Cult of True Womanhood was the importance of the four cardinal virtues for women: piety, purity, submission, and domesticity.

Religion was highly valued in this context, as it did not take women away from their "proper sphere" of the home and was seen as a way to control women's behavior.

Vi-r-g-i-n-i-ty was also highly valued, with women expected to maintain their purity until marriage and to only engage in sexual relations with their husbands afterwards.

Women were expected to be submissive and obedient to men, who were seen as their superiors in the eyes of God. Women were also expected to focus on domestic activities such as housework, needlework, and flower arranging, with other intellectual pursuits discouraged.

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How did the Tet Offensive affect perceptions of the Vietnam War within the United States?

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Answer:

The Tet Offensive affect the public perception because it made the citizen questions the outcome of the Vietnam War.

Explanation:

Hope this helps.

How did Dwight D. Eisenhower background/childhood/decisions help to shape the person they'd eventually became?

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Answer:

Dwight D. Eisenhower grew up in a modest family in Kansas, where he learned the values of hard work and perseverance. His experiences as a young man in the military shaped his leadership style, and he developed a strategic mindset that would serve him well throughout his career. Eisenhower's decisions during World War II and his role in the post-war reconstruction of Germany helped shape him into a respected military leader and statesman.

How many justices are needed to grant cert. for a case to be heard?
a. 5
b. 4
c. 3
d.6

Answers

Answer:

4

Four justices must vote in favor of granting cert

Explanation:

Hope this helps

Explanation: B. 4
If the full Court acts on an application, five Justices must agree in order for the Court to grant a stay, but the votes of only four Justices are required to grant certiorari.

Explain the signifigance of Milgrams obedience study and how it relates to compliance, conformity and the ethics surrounding the experiment. Please explain in around 400 words.

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Under the direction of an experimenter, people were willing to give another person potentially fatal electric shocks, according to Milgram's obedience study. It emphasises how influential environmental influences are in determining behaviour.

What are conformity, obedience, and compliance?

Whereas obedience means doing what you are told, and conformity means caving in to peer pressure or following the crowd, compliance is the act of giving in to an expressed request from another person or group of people.

What was Milgram's research on compliance and obedience?

Stanley Milgram, a social psychologist, studied how respect for authority affected obedience. He came to the conclusion that people, even when acting against their own better judgement and inclinations, obey either out of fear or out of a desire to look cooperative.

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did the black panther party use non-violent tactics?

Answers

Answer:

No.

Explanation:

The black panther party was known for its determination for equal rights at any means necessary.  They would usually resort to violence to get what they wanted.  

Land-based battles in World War I were fought mainly in a.germany b.forested areas c.trenches d.bomb craters

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Option C is the correct option, Trenches . A front is a region of terrain where opposing armies clash and engage in combat.

A front is a region of terrain where opposing armies clash and engage in combat. On the Western Front, a 400+ mile length crisscrossing France, Belgium, and Switzerland, trenches were common. Most British and Irish soldiers who served in World War One fought there. The most common example of trench warfare, which involved digging long, deep ditches as defensive defenses, is World War I, and it had horrible consequences. On the Western Front, trenches were prevalent. The Western Front, a region in northern France and Belgium, was where trench warfare was most commonly used during World War I. After that, they "dug in" to stop losing ground.

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president franklin d roosecelts response to supreme court decisions that decleared several new deal laws unconsitutional was to try and do what

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President Franklin D. Roosevelt's response to Supreme Court decisions that declared several New Deal laws unconstitutional was to propose the Judicial Procedures Reform Bill of 1937, commonly known as the "court-packing plan."

This plan would have allowed the President to appoint up to six new justices to the Supreme Court, effectively shifting the ideological balance in his favor. Roosevelt argued that the additional justices were necessary to speed up the Court's work and address its backlog of cases. However, the plan was met with significant opposition from both Democrats and Republicans, and it ultimately failed to pass through Congress.

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Research the TRAIN LAW, its coverages, and packages. What are the salient features of R.A 10963?

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The TRAIN Law seeks to increase the government's revenue while providing relief to low and middle-income taxpayers. It also aims to promote economic growth by making the tax system more efficient and equitable.

What constitutes the TRAIN law?

The TRAIN Law, or the Tax Reform for Acceleration and Inclusion Law, is a tax reform package in the Philippines that was signed into law on December 19, 2017. The law aims to improve the country's tax system by making it more progressive, efficient, and equitable.

Here are the salient features of R.A 10963, or the TRAIN Law:

1. Personal Income Tax (PIT) Reform: The law adjusted the tax brackets and lowered the PIT rates, resulting in a tax cut for most taxpayers. The new tax rates are as follows:

Annual taxable income up to PHP 250,000: Tax rate is 0%Annual taxable income over PHP 250,000 up to PHP 400,000: Tax rate is 20%Annual taxable income over PHP 400,000 up to PHP 800,000: Tax rate is 25%Annual taxable income over PHP 800,000 up to PHP 2,000,000: Tax rate is 30%Annual taxable income over PHP 2,000,000 up to PHP 8,000,000: Tax rate is 32%Annual taxable income over PHP 8,000,000: Tax rate is 35%

2. Value-Added Tax (VAT) Exemptions: The law exempts certain goods and services from VAT, such as low-cost housing, renewable energy equipment, and healthcare services.

3. Excise Tax on Fuel: The law increased the excise tax on fuel products, which resulted in higher prices of gasoline and diesel.

4. Sugar Sweetened Beverage (SSB) Tax: The law imposed an excise tax on SSBs, such as soda, energy drinks, and sweetened juice drinks.

5. Estate Tax Reform: The law increased the estate tax exemption to PHP 5 million and lowered the estate tax rate to a flat 6%.

6. Documentary Stamp Tax (DST) Reform: The law increased the DST on certain documents, such as loan agreements, deeds of sale, and insurance policies.

Overall, the TRAIN Law seeks to increase the government's revenue while providing relief to low and middle-income taxpayers. It also aims to promote economic growth by making the tax system more efficient and equitable.

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history of china's great wall​

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The history of the Great Wall of China began when fortifications built by various states during the Spring and Autumn and Warring States periods were connected by the first emperor of China, Qin Shi Huang, to protect his newly founded Qin dynasty against incursions by nomads from Inner Asia

How might pluralism serve to enhance democracy’s

Answers

Answer:  by ensuring that all groups have an opportunity to influence policy outcomes.

Explanation:

Do you agree or disagree with the agenda setting theory? Do you think that you pay more attention to social problems that receive attention in the media?
Some scholars have suggested that the media creates a culture of fear because it often focuses on the negative effects that certain social conditions can have. For example, scholars may say that the media may focus on the possibility of an epidemic of an infectious disease when the probability that it will happen is low. Do you think that the media creates a culture of fear? Why or why not?
Where do you get your information about the world from? Do you think you are getting a complete picture of the world and social problems from this source? Why or why not?
Do you think the words and phrases that are used in the media influence the perceptions that you have of events and social problems? Why or why not? What is one example of a word/phrase choice that may affect how people think about a particular social problem?
Do you think that the violence in the media affects individuals in society? Why or why not? Do you think anything should be done about violence in the media? If so, what? If not, why not?

Answers

There is some evidence to suggest that the media can create a culture of fear by focusing on negative and sensationalized news stories.

What is a culture?

Culture refers to shared beliefs, values, customs, behaviors, and the artifacts that characterize a group or society. It encompasses everything from language, religion, and traditions to art, music, and cuisine. Culture is learned and transmitted from one generation to the next, shaping individuals' worldview and guiding their interactions with others. It provides a sense of identity and belonging, influencing people's attitudes, preferences, and actions. Culture is also dynamic and constantly evolving, as people adapt to changing circumstances and encounter new ideas and perspectives. Understanding and respecting cultural diversity is essential for promoting tolerance, mutual respect, and social cohesion in a globalized world.

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The state militia negotiates the provisions of the federal government.
A.) True
B.) False

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false, I don't really know if this is the right answer

Please I need to get this done today

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Option A is correct . Henry IV was able to push for the Gregorian Reform which was a series of reforms initiated by Pope Gregory VII and his circle.

1050–80, which dealt with the moral integrity and independence of the clergy. He also appointed church officials.

What is the Holy Roman Empire?

The Holy Roman Empire was a political entity in Western, Central, and Southern Europe that developed during the Early Middle Ages and continued until its dissolution in 1806 during the Napoleonic Wars. From the accession of Otto I in 962 until the twelfth century, the Empire was the most powerful monarchy in Europe.

The exact term “Holy Roman Empire” was not used until the 13th century, but the Emperor’s legitimacy always rested on the concept of translatio imperii, that he held supreme power inherited from the ancient emperors of Rome.

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Help Please

Do you agree or Disagree and why
The best way to confront colonialism is to present non-European/Western Knowledges.

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Global inequality is increasing Yet, colonialism still exists today. It still persecutes emerging countries and people of color everywhere, from Libya to Western Africa.

What is Western colonialism?

Western colonialism is a political and economic phenomena in which several European countries explored, conquest, settlement, and exploitation of vast tracts of the globe. After The discovery of a sea route around Africa's southern coast (1488) and of America (around 1500), the age of modern colonialism began (1492).

What are the three drawbacks of colonialism?

Among the detrimental effects of colonization are the destruction of natural resources, capitalism, urbanization, and the introduction of foreign illnesses to humans and cattle.

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Daniel Webster of Massachusetts was against the use of slavery but he agreed to compromise on the issue. Why?

He wanted to appeal to the pro-slavery majority of voters in Massachusetts.

He was willing to do almost anything to keep the United States together.

He wanted to run for president and needed southern support.

He was swayed by John C. Calhoun's sound arguments in favor of the use of slavery.

Answers

Answer:

Daniel Webster of Massachusetts was against the use of slavery but he agreed to compromise on the issue. Why?

He wanted to appeal to the pro-slavery majority of voters in Massachusetts.

He was willing to do almost anything to keep the United States together.

He wanted to run for president and needed southern support.

He was swayed by John C. Calhoun's sound arguments in favor of the use of slav

It’s He was swayed by John C. Calhoun’s sound arguments in favor of the use of slavery.


Webster spoke in favor of clay’s compromise proposals that a ban on slavery in the territory acquired from Mexico was not necessary. His support for the compromise doomed his chance for presidency. I had this question in 10th grade.

Martin Luther King Jr. often spoke of a day in the future when he hoped that his children would be judged not by their skin color but instead by their character

Answers

"I have a dream that my 4 little teens will one day live in a state where they will not be judged by way of the coloration of their skin however through the content material of their character.

What used to be Martin Luther King's message about?

Martin Luther King Jr.'s “Dream” speech was a call for equality. It identified the faults of America and what measures had been wished to make it a higher place. A central theme at some stage in the speech was the importance of everybody being dealt with equally.

The main thinking of the speech is to protest towards discrimination and to fight for freedom and equality. It is like a sermon with references to the Bible, the US Constitution, and the Declaration of US Independence.

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How did Greek Democracy work?

Answers

Answer:

Democracy in Ancient Greece was very direct. What this means is that all the citizens voted on all the laws. Rather than vote for representatives, like we do, each citizen was expected to vote for every law. They did have officials to run the government, however. Most of these officials were chosen by a lottery.

Explanation:

What is the anti money laundering aml program

Answers

An Anti-Money Laundering (AML) program is a set of policies, procedures, and internal controls that financial institutions, such as banks, broker-dealers, and money service businesses, establish to detect, prevent, and report instances of money laundering and other financial crimes.

The AML program requires financial institutions to perform customer due diligence (CDD) and ongoing monitoring of their customers to identify suspicious activities and transactions that may indicate money laundering or terrorist financing. Financial institutions are also required to report any suspicious transactions to regulatory authorities.

The AML program is designed to comply with various regulations and laws, such as the Bank Secrecy Act (BSA), which requires financial institutions to maintain adequate records and implement effective AML programs to prevent money laundering and other financial crimes. The AML program is an essential tool for financial institutions to manage the risks associated with money laundering and maintain the integrity of the financial system.

Drag the tiles to the correct boxes to complete the pairs.
Match the descriptions to the names of characters from Roman myths and legends.
Roman Empire's first emperor
led Rome to victory in a day
0000
Romulus
Cincinnatus
Cicero
Augustus
founded the city of Rome
famous orator and Caesar's advisor
s

Answers

Cicero was a well-known orator and Caesar's advisor, while Romulus established Rome and led it to triumph in a single day. The Roman Empire's first emperor was Augustus.

Who in turn were the seven rulers of Rome?

This is a list of Rome's seven kings, or eight if Titus Tatius is included: Tarquinius Priscus, Servius Tullius, Ancus Marcius, Romulus, Tullus Hostilius, and Tarquinius Superbus.

Who was the first king of Rome?

Romulus, so the legend goes, was Rome's first monarch. He performed acts that one would expect of the father of a battle god and the founder of an old city during his fabled reign. He was credited for founding Rome's first political, military, and social institutions as well as with waging war on nearby states.

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what was the result of the worcester v. georgia supreme court case? determine the volume, in ml, of 0.100 m naoh(ag) the student should add to 100. ml of 0.100 m hno (aq) to make a buffer solution with a ph of 3.40. justify your answer. what was lamarck's proposal about organisms? a. that they have an innate (built-in) tendency toward being complex and perfect. selected:b. that they inherit all of the adaptations they display.this answer is incorrect. c. that they belong to species that never change. d. that they have an innate (built-in) tendency to become more simple over time. the emancipation of russian serfs in 1861 [check all that apply] group of answer choices was intended to avert a revolution. brought freedom but few political rights for the peasants. did not significantly increase agricultural production. was achieved at the tsar's insistence. A car was purchased for $33950.00 and is expected to be worth $12950.00 in 7 years. Determine the rate at which the van depreciates in value. Mixed in a drawer are 8 blue socks, 8 white socks, and 2 gray socks. You pull out two socks, one at a time, without looking. Find the probability of getting 2 socks of the same color The probability of getting 2 socks of the same color is the radioactive substance iridium-192 has a half-life of 73.83 days. how many days would it take for a sample of iridium-192 to decay to 10% of its original amount? round your answer to the nearest integer. the process where vendors ship the merchandise prepackaged to the distribution center in the quantities required for each store and then that merchandise is shipped to stores as soon as it is received is called Using the General Knowledge Databases (encyclopedias) and Social Issues and History (Gales) find a piece of information for each question and copy and paste its citation.1. What are the dates of Geoffrey Chaucer's birth and death?2. Find one occupation that Chaucer did besides writing.3. Who was Chaucer's wife?4. For what English king did Chaucer fight in a war against France?5. What do historians believe that Chaucer based the Canterbury Tales on?6. What made The Canterbury Tales different from all other books of its time? Two cakes and three-quarters of another cake were eaten at a party.how do you write this amount as a fraction? in the film example utilizing the hiv virus, viral-inhibiting drugs are essentially doing what in the body? What claim does the author develop about love?A Love and lust produce the same chemicals in the brain, provinthe same feeling.BLove at first sight is something that occurs more often in booksour real lives.Everyone is capable of experiencing love at first sight if they pe what do coral reefs provide to countries that border them? group of answer choices it provides a habitat for many fish species which could be harvested for food a source of income from tourism a more protected coastal environment from large waves and storm surges all of the above 1. What is the area of ABCD?2.What is the length of diagonal BD? What does the underlined word mean in the following sentence?Me acuesto en la cama.I brush my teethI lie downI fall asleepI wake upANSWERS1)B2)C3)A4)B5)D6)A7)B8)C9)D10)B11)A12)B13)A14)B15)A16)B17)C18)D19)A20)B21)B22)B23)C24)B25)D does the average function requires an argument consisting of a series of numbers or a series of cells what are the functions of mitotic cell division? growth of multicellular organisms asexual reproduction cell regeneration production of gametes under absorption costing, fixed overhead is treated like a variable cost because a portion of the total cost is allocated to each unit produced, rather than being expensed as one large sum. true/false My street is _____ noisier than yours. Sometimes, I can't sleep at night because of the noise!a bitlotfarMy hair grows ________ than my brother's. a lot fastermuch more fastermuch fastestLeon is the _________ when he is with his family. (happy)happyhappierhappiestMy mobile phone is ________ than Julio's mobile phone.much more moderna lot modermore lot modernIt _______ warm today, but it's actually quite cold!looksmight becan't beThat ______ be Ella's bag. I think she's got one like that.can'tmustcouldThis _______ be the right building. I'm not sure.can'tcouldn'tmight not which of the following is not an example of a successful crispr-cas application? editing of fix gene to treat hemophilia b treatment of leber's congenital amaurosis editing of a mutation in the gene pcsk9 replacement of factor ix gene in mouse liver cells to cure hemophilia b aav delivery of crispr-cas9 in a mouse model of dmd